Fresh analysis reveals that patients who stop using new weight-loss injections like Wegovy and Mounjaro can put back on reduced body mass far faster than those who stop traditional diet and exercise programs.
Published data in a major health publication demonstrates that while obese individuals can lose about a fifth of their body weight while using the jabs, the weight is regained at an estimated rate of 0.8 kg per month after stopping.
"Users using these medications need to be informed of the risk of quick weight regain when the medication is stopped," cautioned expert Dr. Susan Jebb.
This pace of recovery suggests a reversion to starting weight in about 18 months.
Comparing Therapies
The research, which examined 37 of trials involving over 9,000 of patients, contrasted the outcomes of the injectable medications with other pills.
The team emphasize that individuals who lose weight through dieting usually experience a slower weight regain—approximately 0.1 kg a month—post-intervention.
Understanding the Fast Regain
Doctors suggest the mode of action of the jabs explains the accelerated rebound.
GLP-1 drugs copy a natural hormone called glucagon-like peptide-1, which moderates hunger.
"Sustained high doses of the hormone levels far above than normal might result in the body to produce less of its own natural GLP-1, and may also lessen sensitivity to its effects," noted Dr. Adam Collins, a nutrition specialist.
"Stopping of this medication results in appetite is unsuppressed, making excessive eating far more likely."
A Chronic Condition?
The NHS recommend the injections for people with obesity-related health risks, accompanied by prescribed diet and exercise modifications.
Many experts argue that, considering the likelihood of relapse, the treatment is often ongoing.
This perspective is supported by drug manufacturers, who note that the findings "emphasize the chronic nature of obesity," comparing it to managing diseases like hypertension.
User Accounts
Individuals who have discontinued the medication report a powerful return of hunger.
"It felt as if something flipping and I was suddenly extremely hungry," recalled a patient.
This challenge is worsened if individuals have not developed sustainable lifestyle or habit modifications during therapy.
Growing Use
Recent estimates show that millions of adults in the UK have tried weight-loss jabs in the last 12 months, with desire continuing to grow.
- Adoption is greater among women than males.
- The 40s and 50s age group shows the greatest usage rates.
- A large proportion access the medications through private prescriptions rather than public health services.
In conclusion, experts caution that while the jabs are powerful tools for shedding pounds, they are not a magic cure and lasting health benefits hinges on integrated lifestyle management.
